Pain and Anaesthesia Research Centre

At Barts Health NHS Trust




A selection of publications and presentations since 2010

Wodehouse T, Demopoulos M, Petty R, Miraki-Moud F, Belhaj A, Husband M, Fulton L, Randive N, Oksche A, Mehta V, Gribben J, Langford R. A randomized pilot study to investigate the effect of opioids on immunomarkers using gene expression profiling during surgery. Pain 2019; 160 (12): 2691-2698

May JM, Phillips JP, Fitchat T, Ramaswamy S, Snidvongs S, Kyriacou PA. A novel photoplethysmography sensor for vital signs monitoring from the human trachea. Biosensors 2019, 9 (4), 119

Wodehouse T, Bahra A, Mehta A. Changes in peripheral and central sensitization in patients undergoing occipital nerve stimulation. British Journal of Pain 2019

Wodehouse T, Poply K, Ramaswamy S, Snidvongs S, Bourke J, Tahir H, Ullrich K, Mehta V. A pilot study investigating whether quantitative sensory testing alters after treatment in patients with fibromyalgia. British Journal of Pain 2019; 12 (4): 250-256

Deckers K, De Smedt, Mitchell B, Vivian D, Russo M, Georgius P, Vieceli J, Eldabe S, Gulve A, van Buyten JP, Smet I, Mehta V, Ramaswamy S, Baranidharan G, Sullivan R, Gassin R, Rathmell J, Gilligan C. New therapy for refractory chronic mechanical low back pain - restorative neurostimulation to activate the lumbar multifidus: one year results of a prospective multicenter clinical trial. Neuromodulation 2018; 21 (1): 48-55

Snidvongs S, Taylor RS, Ahmad A, Thomson S, Sharma M, Farr A, Fitzsimmons D, Poulton S, Mehta V, Langford R. Facet-joint injections for non specific low back pain: a feasibility RCT. Health Technology Assessment 2017; 21 (74): 1-130

Mehta V, Snidvongs S, Ghai B, Langford R, Wodehouse T. Characterization of peripheral and central sensitization after dorsal root ganglion intervention in patients with unilateral lumbosacral radicular pain: a prospective pilot study. British Journal of Anaesthesia 2017; 118 (6): 924-931

Farmer AD, Gallagher J, Bruckner-Holt C, Aziz Q.  Narcotic bowel syndrome. Lancet Gastroenterology and Hepatology 2017; 2 (5): 261-368

Sharma C, Long JH, Shah S, Rahman J, Perrett D, Ayoub SS, Mehta V. First evidence of the conversion of paracetamol to AM404 in human cerebrospinal fluid. Journal of Pain Research 2017, 10: 2703-2709

Ramaswamy S, Langford R. Antinociceptive and immunosuppressive effect of opioids in an acute postoperative setting: an evidence-based review. BJA Education 2017; 17 (3); 105-110

Poply K, Mehta V. The dilemma of interventional pain trials: thinking beyond the box. British Journal Of Anaesthesia 2017; 119 (4): 718-719

Morell-Ducos F, Snidvongs S. The abuse potential of opioid formulations. Commissioned by paineurope 2016.

Anjana Reddy VS, Sharma S, Chang K-Y, Mehta V.  ‘Simplicity’ radiofrequency neurotomy of sacroiliac joint: a real life 1-year follow-up UK data.  British Journal of Pain 2016; 10(2): 90-00

Poply K, Bahra A, Mehta V.  Migraine.  BJA Education 2016; 16 (11): 357-361.

Wodehouse T, Bahra A, Ramaswamy S, Casey L, Alamgir A, Van Gronigan R, Mehta V.  Peripheral and central sensitization in patients undergoing occipital nerve stimulator insertion for intractable migraine.  Neuromodulation 2015; 18: 107-399

Alamgir A, Casey L, Ward S, Van Gronigan R, Ramaswamy S, Ellamushi H, Nikolic S, Mehta A.  A prospective evaluation of psychological response to SCS therapy in patients with intractable neuropathic pain.  Neuromodulation 2015; 18, 107-399

Ramaswamy S, Wodehouse T, Casey L, Alamgir A, Ward S, Nikolic S, Van Gronigan R, Ellamushi H, Mehta V.   Peripheral and central sensitization in patients undergoing spinal cord stimulator insertion for chronic neuropathic back and leg pain.  Neuromodulation 2015; 18: 107-399

Ramaswamy S, Chang S, Mehta V. Tapentadol- the evidence so far. Anaesthesia 2015; 70, 518-22

Mehta V, Alawad S, Kuravinakop S, Nikolic S.  Effect of a fixed-dose opioid agonist/antagonist on constipation in patients on long-term opioids for non-malignant pain unable to tolerate laxatives.  Pain Physician 2014; 17: 415-424

Mehta V, Snidvongs S, Langford R, et al.  A prospective open label pilot study to investigate whether quantitative sensory testing correlates with the effectiveness of diagnostic dorsal root ganglion block in patients with unilateral lumbar radiculopathy.  The Journal of Pain.  2013 April; Vol. 14, Issue 4, Supplement, Page S6

Husband M, Mehta V. Cyclo-oxygenase-2 inhibitors. Continuing Education in Anaesthesia, Critical Care & Pain 2013; doi: 10.1093/bjaceaccp/mkt004

Sherren PB, Kong M, Chang S. Comparison of the Macintosh, McCoy, Airtraq laryngoscopes and the intubating laryngeal mask airway in a difficult airway with manual in-line stabilisation: A cross-over, simulation-based study. European Journal of Anaesthesiology 2013; 30(9):544-549

Sharma CV and Mehta V. Paracetamol: mechanisms and updates.  Continuing Education in Anaesthesia, Critical Care & Pain 2013; doi: 10.1093/bjaceaccp/mkt049

Langford RM and Ratcliffe S. A double-blind, randomized, placebo-controlled, parallel-group study of THC/CBD oromucosal spray in combination with the existing treatment regimen, in the relief of central neuropathic pain in patients with multiple sclerosis
Journal of Neurology. 2013. 260(4):984-97   

Mehta V, Casey L, Ghai B, Snidvongs S, Langford RM, Wodehouse T. A Prospective Human Open Label, Pilot Investigation Into Characterizing QST Response Following 5 Hz to DRG. North American Neuromodulation Meeting , Las Vegas 2013

Ramaswamy S, Paul A, Clark V. Two stuck epidural catheters. Anaesthesia 2013, 68, 1274–1287

Ramaswamy S, Wilson JA, Colvin L. Non-opioid-based adjuvant analgesia in perioperative care. Contin Educ Anaesth Crit Care Pain (2013) 13 (5): 152-157

Snidvongs S, Shah S.  Horner’s syndrome following an epidural blood patch.  Journal of the Royal Society of Medicine Short Reports.  2012 Oct; 3: 68; doi: 10.1258/shorts.2012.011135

Snidvongs S, Mehta V.  Recent advances in opioid prescription for chronic non-cancer pain.  Postgraduate Medical Journal.  2012 Feb; 88 (1036): 66-72.

Randive S, Mehta V. Breakthrough pain- novel analgesics. Current Clinical Pharmacology. 2012 May;7(2):116-20

Husband M, Langford RM. Editorial: Advances in pain management. Postgrad Med J 2012;88:57-58 doi:10.1136/postgradmedj-2011-130646

Graven-Nielsen T, Wodehouse T, Langford RM, Arendt-Nielsen L, Kidd, BL. Normalisation of widespread hyperalgesia and facilitated spatial summation of deep-tissue pain in knee osteoarthritis patients after knee replacement. Arthritis & Rheumatism. 2012 Sep;64(9):2907-16. doi: 10.1002/art.344662012

Notcutt, W., Langford, R., Davies, P., Ratcliffe, S., Potts, R. A placebo-controlled, parallel-group, randomized withdrawal study of subjects with symptoms of spasticity due to multiple sclerosis who are receiving long-term Sativex (nabiximols). 2012 Multiple Sclerosis 18(2):219-28

Snidvongs S.  Prolonged-release tapentadol.  Commissioned by Hospital Healthcare Europe.  2012

Mehta V, Alawad S, Kuravinakop S, Nikolic S, Taylor A. Effect of fixed dose opioid agonist/antagonist on constipation in patients on long term opioids for non cancer pain. Journal of Pain 2012 Vol 13 S80

Mehta V, Sharma C, Long J, Shah S, Rahman J, Ayoub S, Perrett D, Langford RM. A Single Centre Prospective Randomised Study to Investigate the Cerebrospinal Fluid (CSF) Pharmacokinetics of Intravenous Paracetamol in Humans. Journal of Pain 2012 Vol 13

Bhukal I, Solanki SL, Ramaswamy S, Yaddanapudi LN, Jain A and Kumar P. Perioperative predictors of morbidity and mortality following cardiac surgery under cardiopulmonary bypass. Saudi J Anaesth 2012 Jul-Sep; 6(3): 242–47

Shah S, Mehta V. Controversies and advances in non-steroidal anti-inflammatory drug analgesia in chronic pain management. Postgrad Med J 2011 doi. 10.1136/postgradmedj-2011-130291

Snidvongs S.  Recent advances in pain management.  Commissioned by Anaesthesia International.  2011

Holdcroft A, Snidvongs S, Berkley K.  Incorporating gender and sex dimensions in medical research.  Gender in Science, Special Issue of Interdisciplinary Science Reviews.  2011 Jun; 36 (2): 180-192.

Mehta V, Siddhalingaiah V. Clinical Examination and Evaluation Cervical Spine. Symptom Oriented Pain Management, 2011. Jaypee Brothers.

Snidvongs S, Holdcroft A.  Women’s response to analgesics.  MIMS Women’s Health.  2010 Jun; 5 (3): 37-39.

Snidvongs S, Mehta V.  Pulsed radiofrequency – a non-neurodestructive therapy in pain management.  Current Opinion in Supportive & Palliative Care.  2010 Jun; 4 (2): 107-110.

Phillips JP, Langford RM, Chang SH, Maney KM, Kyriacou PA, Jones DP. Cerebral arterial oxygen saturation measurements using a fiberoptic pulse oximeter. Neurocritical Care 2010; 13(2): 278-285

Chang SH, Maney KM, Mehta V, Langford RM. Pain Assessment and Management in Medical Wards: an area of unmet need. Postgrad Med J. 2010 May; 86 (1015): 279-84

Chang SH, Maney KM, Phillips JP, Langford RM, Mehta V. A prospective, randomised, double-blind, placebo-controlled investigation of the respiratory effects of oxycodone versus morphine in anesthetised patients. 2010 65(10): 1007-1012

Mehta V, Shah S. Paracetamol- the forgotten drug. 2010 Br J Hosp Med 71 (11); 606-7

Holder E1, Stevenson B, Farley R, Hilliard T, Wodehouse T, et al.  Detection of CFTR transgene mRNA expression in respiratory epithelium isolated from the murine nasal cavity.  J Gene Med. 2010 Jan;12(1):55-63. doi: 10.1002/jgm.1413.

M Hickey, N Samuels, N Randive, R M Langford, and P A Kyriacou. Measurement of splanchnic photoplethysmographic signals using a new reflectance fibre-optic sensor. Journal of Biomedical Optics. 2010.15, 027012

Chang SH, Maney KM, Mehta V, Langford RM. Survey of acute pain service involvement in medical wards in UK hospitals. Postgraduate Medical Journal 2010; 86 (1015): 279-284